What is the best virus software in your opinion?

I don't think there's an antivirus that can be deemed as best, but the one that seems to suit me well is Eset's NOD32. It doesn't require too many resources, it's updated quite often and it does its job quietly. It may not be the fastest when doing a virus scan but it's no snail either .

There is in my opinion no "best virus scanner", all virus scanners have something which makes them good or better. I myself am using AVG free, updates frequently, isn't slow (like Norton/McAfee) and scans fast. For a free virus scanner, I think AVG will win the contest.